CD56 antibody (10R-8095)

Mouse monoclonal CD56 antibody

Synonyms Monoclonal CD56 antibody, Anti-CD56 antibody, LFA3 antibody, CD56
Cross Reactivity Human, Zebrafish
Applications IHC, IHC-F, IHC-P, WB
Immunogen CD56 antibody was raised in Mouse using the a membrane preparation of a small cell lung carcinoma specimen as the immunogen.

Specifications

Host Mouse
Clone 123C3
Isotype IgG1
Form & Buffer Supplied in PBS containing 0.09% sodium azide

Usage & Assay Information

Usage Recommendations IHC: 1:100-1:200, WB: 1:100-1:1000

General Information

Biological Significance NCAM, as a member of the immunoglobulin superfamily of adhesion molecules is characterized by several immunoglobulin (Ig)-like domains. The extracellular part of NCAM consists of five of these Ig domains and two fibronectin type III homology regions. NCAM is encoded by a single copy gene composed of 26 exons. However, at least 20-30 distinct isoforms can be generated by alternative splicing and by posttranslational modifications, such as sialylation. During sialylation, polysialic acid (PSA) carbohydrates are attached to the extracellular part of NCAM. Through its extracellular region, NCAM mediates homophilic interactions. In addition, NCAM can also undergo heterophilic interactions by binding extracellular matrix components, such as laminin, or other cell adhesion molecules, such as integrins.

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Availability: In stock

Price: $375.00
Size: 100 ug
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