CD8 antibody (10R-1881)
Mouse monoclonal CD8 antibody
|Synonyms||Monoclonal CD8 antibody, Anti-CD8 antibody, CD8, CD 8 antibody, CD-8 antibody, CD-8, CD 8, Cluster of differentiation 8 antibody|
|Applications||ELISA, FC, WB|
|Immunogen||CD8 antibody was raised in Mouse using a purified recombinant fragment of human CD8 expressed in E. coli as the immunogen.|
Flow Cytometric assay using (CD8 antibody)
FC analysis of blood T cells using CD8 antibody (M2) and negative control (M1).
|Form & Buffer||Purified antibody supplied in PBS containing 0.03% sodium azide.|
Usage & Assay Information
|Usage Recommendations||ELISA: 1:10,000, FC: 1:200-1:400, WB: 1:500-1:2000|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||CD8 is a transmembrane glycoprotein that serves as a co-receptor for the T cell receptor (TCR). Like the TCR, CD8 binds to a major histocompatibility complex (MHC) molecule, but is specific for the class I MHC protein. There are two isoforms of the protein, alpha and beta, each encoded by a different gene. In humans, both genes are located on chromosome 2 in position 2p12.|
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