CD86 antibody (10R-2252)
Mouse monoclonal CD86 antibody
|Synonyms||Monoclonal CD86 antibody, Anti-CD86 antibody, CD86 antigen antibody, CD86, CD 86, CD 86 antibody, Cluster of Differentiation 86 antibody, B72 antibody, T-lymphocyte activation antigen CD86 antibody, Cluster of differentiation 86 antibody, B 72 antibody, CTLA-4 counter-receptor B7.2 antibody, CD-86 antibody, B-lymphocyte activation antigen B7 2 antibody, CD-86|
|Immunogen||CD86 antibody was raised in Mouse using a purified recombinant fragment of human CD86 expressed in E. coli as the immunogen.|
Western Blot analysis using CD86 antibody (10R-2252)
Western Blot showing CD86 antibody used against L1210 (1) and MOLT-4 (2) cell lysate.
|Form & Buffer||Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.|
Usage & Assay Information
|Usage Recommendations||ELISA: 1:10,000, WB: 1:200-1:1000|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||CD86 is a protein expressed on antigen-presenting cells that provides costimulatory signals necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28 (for autoregulation and intercellular association) and CTLA4 (for attenuation of regulation and cellular disassociation). CD86 works in tandem with CD80 to prime T cells.|
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