CDC2 antibody (10R-1589)

Mouse monoclonal CDC2 antibody

Synonyms Monoclonal CDC2 antibody, Anti-CDC2 antibody, CDC 2 antibody, Cyclin dependent kinase 1 antibody, CDC2, CDK1 antibody, DKFZp686L20222 antibody, CDC28A antibody, CDC-2 antibody, CDC 2, CDC-2, MGC111195 antibody
Specificity Human CDC2
Cross Reactivity Human, Mouse, Rat. Other species not studied
Applications Dot Blot, WB
Immunogen CDC2 antibody was raised in mouse using recombinant Human Cell Division Cycle 2, G1 To S And G2 To M (Cdc2)

Images

Western Blot analysis of immunized recombinant protein using CDC2 antibody (10R-1589)

Specifications

Host Mouse
Clone 2130C1a
Isotype IgG1
Method of Purification CDC2 antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Form & Buffer CDC2 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3 ).
Concentration 100 ug/ml

Usage & Assay Information

Usage Recommendations WB: 0.2-2 ug/ml

Storage & Safety

Storage Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing.
Biohazard Information This antibody solution contains sodium azide (NaN ) as a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water. It is strongly adv

General Information

Biological Significance The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.

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Images

  • Western Blot analysis of immunized recombinant protein using CDC2 antibody (10R-1589)

Availability: In stock

Price: $190.00
Size: 50 ug
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