CDC2 antibody (70R-10474)

Affinity purified rabbit polyclonal CDC2 antibody

Synonyms Polyclonal CDC2 antibody, Anti-CDC2 antibody, CDC 2, CDK1 antibody, DKFZp686L20222 antibody, CDC28A antibody, CDC2, cell division cycle 2, CDC-2, G1 to S and G2 to M antibody, CDC-2 antibody, MGC111195 antibody, CDC 2 antibody
Cross Reactivity Human
Applications IHC, WB
Immunogen CDC2 antibody was raised in rabbit using the C terminal of CDC2 as the immunogen
Assay Information CDC2 Blocking Peptide, catalog no. 33R-8578, is also available for use as a blocking control in assays to test for specificity of this CDC2 antibody

Images

Immunohistochemical staining using CDC2 antibody (70R-10474)

Human kidney

Specifications

Host Rabbit
Form & Buffer Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 0.1 ug/ml

Storage & Safety

Storage Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.

General Information

Biological Significance The protein encoded by CDC2 is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.

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Images

  • Immunohistochemical staining using CDC2 antibody (70R-10474) | Human kidney
  • Western blot analysis using CDC2 antibody (70R-10474) | Recommended CDC2 Antibody Titration: 0.1ug/ml

Availability: In stock

Price: $345.00
Size: 50 ug
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