CDC42 antibody (70R-10438)

Affinity purified rabbit polyclonal CDC42 antibody

Synonyms Polyclonal CDC42 antibody, Anti-CDC42 antibody, 25kDa antibody, CDC42Hs antibody, CDC 42, CDC42, CDC-42, GTP binding protein, cell division cycle 42, CDC 42 antibody, G25K antibody, CDC-42 antibody
Cross Reactivity Human, Mouse, Rat, Chicken, Dog
Applications WB
Immunogen CDC42 antibody was raised in rabbit using the N terminal of CDC42 as the immunogen
Assay Information CDC42 Blocking Peptide, catalog no. 33R-2092, is also available for use as a blocking control in assays to test for specificity of this CDC42 antibody

Images

Western blot analysis using CDC42 antibody (70R-10438)

Recommended CDC42 Antibody Titration: 0.2-1 ug/ml

Specifications

Host Rabbit
Form & Buffer Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 0.2-1 ug/ml

Storage & Safety

Storage Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.

General Information

Biological Significance CDC42 is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants.

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Images

  • Western blot analysis using CDC42 antibody (70R-10438) | Recommended CDC42 Antibody Titration: 0.2-1 ug/ml

Availability: In stock

Price: $345.00
Size: 50 ug
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