CDC45L antibody (10R-1302)

Mouse monoclonal CDC45L antibody

Synonyms Monoclonal CDC45L antibody, Anti-CDC45L antibody, CDC-45L antibody, CDCL 45, CDC45 antibody, CDC 45L antibody, CDC-45L, PORC-PI-1 antibody, CDC45L, CDC45L2 antibody, Cell division cycle 45 homolog antibody
Specificity Human CDC45L
Cross Reactivity Human. Other species not studied
Applications Dot Blot
Immunogen CDC45L antibody was raised in mouse using recombinant Human Cdc45 Cell Division Cycle 45-Like (S. Cerevisiae) (Cdc45L)

Images

Western Blot analysis of immunized recombinant protein using CDC45L antibody (10R-1302)

Specifications

Host Mouse
Clone 2135C1a
Isotype IgG1
Method of Purification CDC45L antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Form & Buffer CDC45L antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3 ).
Concentration 100 ug/ml

Usage & Assay Information

Usage Recommendations To be optimized by the end user.

Storage & Safety

Storage Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing.
Biohazard Information This antibody solution contains sodium azide (NaN ) as a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water. It is strongly adv

General Information

Biological Significance The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin.

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Images

  • Western Blot analysis of immunized recombinant protein using CDC45L antibody (10R-1302)

Availability: In stock

Price: $190.00
Size: 50 ug
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