CDK5 antibody (10R-8355)

Mouse monoclonal CDK5 antibody

Synonyms Monoclonal CDK5 antibody, Anti-CDK5 antibody, CDK 5 antibody, CDK-5 antibody, CDK5, Cell division protein kinase 5 antibody, Crk6 antibody, Cyclin dependent kinase 5 antibody, Protein kinase CDK5 splicing antibody, PSSALRE antibody, Serine threonine protein kinase PSSALRE antibody, Tau protein kinase II catalytic subunit antibody, TPKII catalytic subunit antibody
Applications IHC, WB

Images

Western Blot analysis using CDK5 antibody (10R-8355)

Western blot of rat caudate lysate showing specific immunolabeling of ~ 28k Cdk5 protein

Specifications

Host Mouse
Clone 1H3
Isotype IgG1
Method of Purification CDK5 antibody was purified by Protein G affinity chromatography
Form & Buffer Supplied in liquid form in 10 mM HEPES buffer (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:1000, IHC: 1:500

General Information

Biological Significance Cell division protein kinase 5 is an enzyme that in humans is encoded by the CDK5 gene. The protein encoded by this gene is part of the cyclin-dependent kinase family. Recently Cdk5 has emerged as an essential kinase in sensory pathways. Recent reports of Pareek et al. from NIH suggest its necessity in pain signaling. CDK5 is required for proper development of the brain and to be activated, CDK5 must associate with CDK5R1 or CDK5R2. Unlike other cyclin dependent kinases, CDK5 does not also require phosphorylation on the T loop so that binding with the activator is sufficient to activate the kinase.

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Images

  • Western Blot analysis using CDK5 antibody (10R-8355) | Western blot of rat caudate lysate showing specific immunolabeling of ~ 28k Cdk5 protein

Availability: In stock

Price: $335.00
Size: 100 ul
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