CDK5 antibody (20R-3001)

Rabbit polyclonal CDK5 antibody

Synonyms Polyclonal CDK5 antibody, Anti-CDK5 antibody, CDK5 antibody, cyclin-dependent kinase 5 antibody, BOS_4735 antibody, Cdk5-PA antibody, cell division protein kinase 5 antibody, CG8203-PA antibody, CR6 protein kinase antibody, Crk6 antibody, cyclin-dependent protein kinase 5 antibody, DmCdk5 antibody, Dmel_CG8203 antibody, neuronal cyclin-dependent kinase 5 antibody, NV14994 antibody, PDPK antibody, proline-directed protein kinase 33 kDa subunit antibody, protein kinase CDK5 splicing antibody, pssalre antibody, serine/threonine-protein kinase PSSALRE antibody, tau protein kinase II catalytic subunit antibody, TPKII catalytic subunit antibody
Cross Reactivity Human, Mouse, Rat
Applications WB
Immunogen CDK5 antibody was raised in Rabbit using a His-tagged recombinant human CDK5 protein purified from Baculovirus expressed insect cells as the immunogen

Images

Western Blot analysis using CDK5 antibody (20R-3001)

Specifications

Host Rabbit
Isotype IgG
Method of Purification CDK5 antibody was purified by Protein A affinity chromatography
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:500-1000

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance CDK5 is a member of the cyclin-dependent kinase family of serine/threonine kinases. Its mRNA and protein are expressed in the kidneys, testes, and ovaries. And Its activity has been detected almost exclusively in brain extracts. Similar to other Cdks, monomeric Cdk5 displays no enzymatic activity; however, Cdk5 is not activated by cyclins. Instead, Cdk5 activity requires association with one of two brain-specific regulatory subunits, called p35 and p39. These two activators regulate the spatial and temporal expression of active Cdk5, restricting its activity primarily to post-mitotic neurons.

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Images

  • Western Blot analysis using CDK5 antibody (20R-3001) |

Availability: In stock

Price: $295.00
Size: 100 ul
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