CDK7 antibody (10R-8530)

Mouse monoclonal CDK7 antibody

Synonyms Monoclonal CDK7 antibody, Anti-CDK7 antibody, CDK7 antibody, cyclin-dependent kinase 7 antibody, 39 KDa protein kinase antibody, 39 protein kinase antibody, 40 kDa protein kinase antibody, BOS_19697 antibody, C230069N13 antibody, CAK antibody, CAK1 antibody, CD 7 antibody, CDC2/CDK2 antibody,4-activating kinase antibody, cdk-7 antibody, Cdk7-PA antibody, CDK-activating kinase antibody, CDK-activating kinase 1 antibody, cdkn7 antibody, Cell division protein kinase 7 antibody, CG3319-PA antibody, CR4 protein kinase antibody, Crk4 antibody, CRK4 PK (CDC2-related-kinase-4 protein kinase) antibody, cyclin dependent kinase 7 antibody, cyclin-dependent kinase 7 (homolog of Xenopus MO15 cdk-activating kinase) antibody, cyclin-dependent kinase 7 (MO15 antibody, cdk-activating kinase) antibody, cyclin-dependent kinase 7 (MO15 homolog Xenopus laevis cdk-activating kinase) antibody, cyclin-dependent kinase 7 (MO15 homolog antibody, Xenopus laevis antibody, cdk-activating kinase) antibody, dCdk7 antibody, DmCDK7 antibody, Dmel_CG3319 antibody, DmMo15 antibody, HCAK antibody, homolog of Xenopus MO15 Cdk-activating kinase antibody, kinase subunit of CAK antibody, MO15 antibody, p39mo15 antibody, P39 Mo15 antibody, p40MO15 antibody, p40[MO15] antibody, P40 MO15 antibody, protein kinase antibody, protein-tyrosine kinase MPK-7 antibody, serine/threonine kinase stk1 antibody, serine/threonine protein kinase 1 antibody, serine/threonine-protein kinase 1 antibody, serine/threonine protein kinase MO15 antibody, STK1 antibody, TFIIH basal transcription factor complex kinase subunit antibody
Cross Reactivity Human
Applications ELISA, IP, WB
Immunogen CDK7 antibody was raised in Mouse using a recombinant human protein purified from E.coli(His/ABD-CDK7 136-346 a.a.) as the immunogen

Images

Western Blot analysis using CDK7 antibody (10R-8530)

Specifications

Host Mouse
Clone 45H1
Isotype IgG2b kappa
Method of Purification CDK7 antibody was purified by ammonium sulfate precipitation
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:2000-5000, IP: 1 ul

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance CDK7 forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK), phosphorylating cell-cycle CDKs. It is also an essential component of the transcription factor TFIIH, which phosphorylates the C-terminal domain (CTD) of the largest subunit of Pol II. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle. Embryonic stem cells (ESCs) shows a very unusual cell cycle structure, characterized by a short G1 phase and a high proportion of cells in S-phase. This is associated with a unique mechanism of cell cycle regulation by the activity of cyclin dependent protein kinase (Cdk).

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Images

  • Western Blot analysis using CDK7 antibody (10R-8530) |

Availability: In stock

Price: $295.00
Size: 100 ul
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