CDK9 antibody (10R-1572)

Mouse monoclonal CDK9 antibody

Synonyms Monoclonal CDK9 antibody, Anti-CDK9 antibody, CDK9, PITALRE antibody, TAK antibody, CDK-9 antibody, CDK 9, CDK-9, CDC2L4 antibody, CDK 9 antibody, Cyclin dependent kinase 9 antibody, C-2k antibody
Specificity Human CDK9
Cross Reactivity Human, Mouse, Rat. Other species not studied
Applications Dot Blot, WB
Immunogen CDK9 antibody was raised in mouse using recombinant Human Cyclin-Dependent Kinase 9 (Cdc2-Relatedkinase)(Cdk9)

Images

Western Blot analysis of immunized recombinant protein using CDK9 antibody (10R-1572)

Specifications

Host Mouse
Clone 2142C1a
Isotype IgG1
Method of Purification CDK9 antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Form & Buffer CDK9 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3 ).
Concentration 100 ug/ml

Usage & Assay Information

Usage Recommendations WB: 0.2-2 ug/ml

Storage & Safety

Storage Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing.
Biohazard Information This antibody solution contains sodium azide (NaN ) as a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water. It is strongly adv

General Information

Biological Significance The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.

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Images

  • Western Blot analysis of immunized recombinant protein using CDK9 antibody (10R-1572)

Availability: In stock

Price: $190.00
Size: 50 ug
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