CDK9 antibody (70R-10466)
Affinity purified rabbit polyclonal CDK9 antibody
|Synonyms||Polyclonal CDK9 antibody, Anti-CDK9 antibody, CDK-9, CDC2L4 antibody, CDK-9 antibody, TAK antibody, cyclin-dependent kinase 9 antibody, PITALRE antibody, CDK9, C-2k antibody, CDK 9, CDK 9 antibody|
|Immunogen||CDK9 antibody was raised in rabbit using the N terminal of CDK9 as the immunogen|
Western Blot analysis using CDK9 antibody (70R-10466)
CDK9 antibody (70R-10466) used at 0.2-1 ug/ml to detect target protein.
|Form & Buffer||Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.|
Usage & Assay Information
|Usage Recommendations||WB: 0.2-1 ug/ml|
Storage & Safety
|Storage||Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.|
|Biological Significance||CDK9 is the member of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex, also called positive transcription elongation factor b (P-TEFb), which facilitates the transition from abortive to production elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II), SUPT5H and RDBP. The CDK9/cyclin-K complex has also a kinase activity toward CTD of RNAP II and can substitute for P-TEFb in vitro.|
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