CDKN1B antibody (10R-1573)

Mouse monoclonal CDKN1B antibody

Synonyms Monoclonal CDKN1B antibody, Anti-CDKN1B antibody, CDKN4 antibody, CDKN1B, KIP1 antibody, CDKNB 1 antibody, MEN4 antibody, MEN1B antibody, CDKNB 1, CDKNB-1, P27KIP1 antibody, Cyclin dependent kinase inhibitor 1B antibody, CDKNB-1 antibody
Specificity Human CDKN1B
Cross Reactivity Human, Mouse, Rat. Other species not studied
Applications Dot Blot, WB
Immunogen CDKN1B antibody was raised in mouse using recombinant Human Cyclin-Dependent Kinase Inhibitor 1B (P27, Kip1) (Cdkn1B)

Images

Western Blot analysis of immunized recombinant protein using CDKN1B antibody (10R-1573)

Specifications

Host Mouse
Clone 2144C8a
Isotype IgG1
Method of Purification CDKN1B antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Form & Buffer CDKN1B antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3 ).
Concentration 100 ug/ml

Usage & Assay Information

Usage Recommendations WB: 0.2-2 ug/ml

Storage & Safety

Storage Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing.
Biohazard Information This antibody solution contains sodium azide (NaN ) as a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water. It is strongly adv

General Information

Biological Significance This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state.

References
Add a Paper

Sorry, but there are no references currently for this product.

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Images

  • Western Blot analysis of immunized recombinant protein using CDKN1B antibody (10R-1573)

Availability: In stock

Price: $190.00
Size: 50 ug
OR
Shipping
View Our Distributors