CDKN2B antibody (70R-10487)

Affinity purified rabbit polyclonal CDKN2B antibody

Synonyms Polyclonal CDKN2B antibody, Anti-CDKN2B antibody, CDKN2B, CDKNB 2, cyclin-dependent kinase inhibitor 2B, inhibits CDK4 antibody, CDKNB-2, p15, CDKNB-2 antibody, CDKNB 2 antibody
Cross Reactivity Human, Mouse, Rat, Bovine, Pig, Dog
Applications WB
Immunogen CDKN2B antibody was raised in rabbit using the middle region of CDKN2B as the immunogen
Assay Information CDKN2B Blocking Peptide, catalog no. 33R-7871, is also available for use as a blocking control in assays to test for specificity of this CDKN2B antibody

Images

Western Blot analysis using CDKN2B antibody (70R-10487)

CDKN2B antibody (70R-10487) used at 0.2-1 ug/ml to detect target protein.

Specifications

Host Rabbit
Form & Buffer Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 0.2-1 ug/ml

Storage & Safety

Storage Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.

General Information

Biological Significance CDKN2B's gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. CDKN2B is a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition.

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Images

  • Western Blot analysis using CDKN2B antibody (70R-10487) | CDKN2B antibody (70R-10487) used at 0.2-1 ug/ml to detect target protein.

Availability: In stock

Price: $345.00
Size: 50 ug
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