CDKN2C protein (His tag) (80R-2119)

Recombinant human CDKN2C protein (His tag)

Synonyms CDKN-2C, CDKN 2C protein, CDKN 2C, INK4C protein, Cyclin-dependent kinase 4 inhibitor C protein, CDKN2C, p18 protein, p18-INK4C protein, CDKN-2C protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of CDKN2C protein (His tag) (80R-2119)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 1-168 amino acids: MGSSHHHHHH SSGLVPRGSH MGSHMAEPWG NELASAAARG DLEQLTSLLQ NNVNVNAQNG FGRTALQVMK LGNPEIARRL LLRGANPDLK DRTGFAVIHD AARAGFLDTL QTLLEFQADV NIEDNEGNLP LHLAAKEGHL RVVEFLVKHT ASNVGHRNHK GDTACDLARL YGRNEVVSLM QANGAGGATN LQ
Expression System E.coli
Purity > 95% pure
Molecular Weight 20.7 kDa (192aa), confirmed by MALDI-TOF
Tag/Conjugate His tag
Form & Buffer Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 10% glycerol, 200mM NaCl
Concentration 0.5 mg/ml

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Can be stored at 4 deg C short term (1-2 weeks). For long term storage, aliquot and store at -20 deg C or -70 deg C. Avoid repeated freezing and thawing cycles.

General Information

Biological Significance CDKN2C (Cyclin-dependent kinase 4 inhibitor C ) belongs to the CDKN2 cyclin-dependent kinase inhibitor family. It has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. And this protein suppresses the cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Recombinant human CDKN2C protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

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Images

  • Coomassie Blue stained SDS-PAGE of CDKN2C protein (His tag) (80R-2119) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: $270.00
Size: 100 ug
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