CEA protein (in TRIS) (30-AC26)

Purified native Human CEA protein

Synonyms Carcinoembryonic Antigen protein
Species Human
Protein Type Native
Applications ELISA

Specifications

Source Purified human liver carcinoma
Purity > 80% pure
Form & Buffer Supplied in 20mM TRIS-HClwith0.05% NaN3.
Concentration Batch dependent - please inquire should you have specific requirements

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Aliquot and store at -20 deg C. Avoid repeated freeze/thaw cycles
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

General Information

Biological Significance Carcinoembryonic antigen (CEA) is a glycoprotein involved in cell adhesion. It is normally produced during fetal development, but the production of CEA stops before birth. Therefore, it is not usually present in the blood of healthy adults, although levels are raised in heavy smokers. CEA is a glycosyl phosphatidyl inositol (GPI)-cell surface anchored glycoprotein whose specialized sialofucosylated glycoforms serve as functional colon carcinoma L-selectin and E-selectin ligands, which may be critical to the metastatic dissemination of colon carcinoma cells.

References
Add a Paper

Jose Lima, Connie Jenkins, Antonio Guerrero, Pierre L. Triozzi, Denise R. Shaw, Theresa V. Strong

A DNA vaccine encoding genetic fusions of carcinoembryonic antigen (CEA) and granulocyte/macrophage colony-stimulating factor (GM-CSF)

Vaccine

Volume: 23 Issue: 10 Page: 1273-1283 DOI: 10.1016/j.vaccine.2004.08.043

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Availability: In stock

Price: $355.00
Size: 1 mg
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