CEBPA antibody (10R-1556)

Mouse monoclonal CEBPA antibody

Synonyms Monoclonal CEBPA antibody, Anti-CEBPA antibody, CEBP antibody, CCAAT/enhancer binding protein (C/EBP) alpha antibody, C/EBP-alpha antibody
Specificity Human CEBPA
Cross Reactivity Human. Other species not studied
Applications Dot Blot
Immunogen CEBPA antibody was raised in mouse using recombinant Human Ccaat/Enhancer Binding Protein (C/Ebp), Alpha

Images

Western Blot analysis of immunized recombinant protein using CEBPA antibody (10R-1556)

Specifications

Host Mouse
Clone 52D6a
Isotype IgG1
Method of Purification CEBPA antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Form & Buffer CEBPA antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3 ).
Concentration 100 ug/ml

Usage & Assay Information

Usage Recommendations To be optimized by the end user.

Storage & Safety

Storage Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing.
Biohazard Information This antibody solution contains sodium azide (NaN ) as a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water. It is strongly adv

General Information

Biological Significance The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.

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Images

  • Western Blot analysis of immunized recombinant protein using CEBPA antibody (10R-1556)

Availability: In stock

Price: $190.00
Size: 50 ug
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