CENPC1 antibody (10R-1328)

Mouse monoclonal CENPC1 antibody

Synonyms Monoclonal CENPC1 antibody, Anti-CENPC1 antibody, CENP-1c antibody, CENPC antibody, CENPC1, CENP 1c, MIF2 antibody, CENP 1c antibody, CENP-1c, Centromere protein C1 antibody, hcp-4 antibody, CENP-C antibody
Specificity Human CENPC1
Cross Reactivity Human. Other species not studied
Applications Dot Blot
Immunogen CENPC1 antibody was raised in mouse using recombinant Human Centromere Protein C 1 (Cenpc1)

Images

Western Blot analysis of immunized recombinant protein using CENPC1 antibody (10R-1328)

Specifications

Host Mouse
Clone 2159C5a
Isotype IgG2b
Method of Purification CENPC1 antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Form & Buffer CENPC1 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3 )
Concentration 100 ug/ml

Usage & Assay Information

Usage Recommendations To be optimized by the end user.

Storage & Safety

Storage Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing.
Biohazard Information This antibody solution contains sodium azide (NaN ) as a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water. It is strongly adv

General Information

Biological Significance CENPC1 is a component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPC recruits DNA methylation and DNMT3B to both centromeric and pericentromeric satellite repeats and regulates the histone code in these regions.

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Images

  • Western Blot analysis of immunized recombinant protein using CENPC1 antibody (10R-1328)

Availability: In stock

Price: $190.00
Size: 50 ug
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