CENPH antibody (70R-5517)

Rabbit polyclonal CENPH antibody raised against the middle region of CENPH

Synonyms Polyclonal CENPH antibody, Anti-CENPH antibody, NNF1 antibody, Centromere Protein H antibody, PMF1 antibody
Specificity CENPH antibody was raised against the middle region of CENPH
Cross Reactivity Human
Applications WB
Immunogen CENPH antibody was raised using the middle region of CENPH corresponding to a region with amino acids ESWDLEEKLLDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENSERI
Assay Information CENPH Blocking Peptide, catalog no. 33R-2751, is also available for use as a blocking control in assays to test for specificity of this CENPH antibody

Images

Western Blot analysis using CENPH antibody (70R-5517)

CENPH antibody (70R-5517) used at 1 ug/ml to detect target protein.

Specifications

Host Rabbit
Method of Purification Affinity purified
Molecular Weight 27 kDa (MW of target protein)
Form & Buffer Lyophilized powder. Add 50ul distilled water for a 1mg/ml concentration of CENPH antibody in PBS
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1 ug/ml

Storage & Safety

Storage Store at 2-8 deg C for short periods. For longer periods of storage, store at -20 deg C. Avoid repeat freeze-thaw cycles.

General Information

Biological Significance Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. CENPH colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex.

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  • Western Blot analysis using CENPH antibody (70R-5517) | CENPH antibody (70R-5517) used at 1 ug/ml to detect target protein.

Availability: In stock

Price: $345.00
Size: 50 ug
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