CENPM protein (His tag) (80R-2949)
Purified recombinant KLF3 protein (His tag)
|Synonyms||Centromere M isoform a protein, bK250D10.2 protein, C22orf18 protein, CENP-M protein, PANE1 protein|
SDS-PAGE analysis of CENPM protein (His Tag) (80R-2949)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-180 aa: MGSSHHHHHH SSGLVPRGSH MGSMSVLRPL DKLPGLNTAT ILLVGTEDAL LQQLADSMLK EDCASELKVH LAKSLPLPSS VNRPRIDLIV FVVNLHSKYS LQNTEESLRH VDASFFLGKV CFLATGAGRE SHCSIHRHTV VKLAHTYQSP LLYCDLEVEG FRATMAQRLV RVLQICAGHV PGVSALNLLS LLRSSEGPSL EDL|
|Purity||> 85% pure|
|Molecular Weight||22 kDa|
|Form & Buffer||Supplied in liquid form in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol, 1mM DTT.|
Storage & Safety
|Storage||Store at 4 deg C for up to 2 weeks. For long term storage, aliquot and store at -20 deg C to -70 deg C. Avoid repeated freeze/thaw cycles|
|Biological Significance||The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays nucleosomes in which CENPA replaces histone H3. CENPM is an additional factor required for centromere assembly.|
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