CHCHD3 protein (His tag) (80R-3511)
Purified recombinant CHCHD3 protein (His tag)
|Synonyms||MINOS3 protein, PPP1R22 protein, CHCHD 3 protein, CHCHD-3 protein|
Coomassie blue stained SDS-PAGE of CHCHD3 protein (His tag) (80R-3511)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-227 aa: MGSSHHHHHH SSGLVPRGSH MGSMGGTTST RRVTFEADEN ENITVVKGIR LSENVIDRMK ESSPSGSKSQ RYSGAYGASV SDEELKRRVA EELALEQAKK ESEDQKRLKQ AKELDRERAA ANEQLTRAIL RERICSEEER AKAKHLARQL EEKDRVLKKQ DAFYKEQLAR LEERSSEFYR VTTEQYQKAA EEVEAKFKRY ESHPVCADLQ AKILQCYREN THQTLKCSAL ATQYMHCVNH AKQSMLEKGG|
|Purity||> 80% pure|
|Method of Purification||CHCHD3 protein was purified by using conventional chromatography techniques|
|Molecular Weight||28.5 kDa|
|Form & Buffer||Supplied in liquid form in 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 2mM DTT|
Storage & Safety
|Storage||Can be stored at 4 deg C short term (1-2 weeks). For long term storage, aliquot and store at -20 deg C or -70 deg C. Avoid repeated freezing and thawing cycles.|
|Biological Significance||Coiled-coil-helix-coiled-coil-helix domain containing protein 3, also known as CHCHD3, is required for maintenance of mitochondrial crista integrity and mitochondrial function. This protein may act as a scaffolding protein that stabilizes protein complexes involved in crista architecture and protein import. It has also been shown to function as a transcription factor which binds to the BAG1 promoter and represses BAG1 transcription.|
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