CHD3 antibody (10R-1364)

Mouse monoclonal CHD3 antibody

Synonyms Monoclonal CHD3 antibody, Anti-CHD3 antibody, Mi2-ALPHA antibody, CHD-3 antibody, Mi-2a antibody, CHD-3, CHD3, ZFH antibody, CHD 3 antibody, Chromodomain-helicase-DNA-binding protein 3 antibody, CHD 3
Specificity Human CHD3
Cross Reactivity Human. Other species not studied
Applications Dot Blot
Immunogen CHD3 antibody was raised in mouse using recombinant Human Chromodomain Helicase Dna Binding Protein 3 (Chd3)

Images

Western Blot analysis of immunized recombinant protein using CHD3 antibody (10R-1364)

Specifications

Host Mouse
Clone 2172C1a
Isotype IgG1
Method of Purification CHD3 antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Form & Buffer CHD3 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3 ).
Concentration 100 ug/ml

Usage & Assay Information

Usage Recommendations To be optimized by the end user.

Storage & Safety

Storage Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing.
Biohazard Information This antibody solution contains sodium azide (NaN ) as a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water. It is strongly adv

General Information

Biological Significance This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis.

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Images

  • Western Blot analysis of immunized recombinant protein using CHD3 antibody (10R-1364)

Availability: In stock

Price: $190.00
Size: 50 ug
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