CHI3L1 protein (His tag) (80R-2666)
Purified recombinant Human CHI3L1 protein (His tag)
|Synonyms||GP39 protein, CHIL1 3, CHIL1-3, CHIL1-3 protein, CHIL1 3 protein, ASRT7 protein, HCGP-3P protein, YKL40 protein, YYL-40 protein, Chitinase 3-like 1 protein, CHI3L1, HC-gp39 protein|
SDS-PAGE analysis of CHI3L1 protein (His tag) (80R-2666)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-383 aa: MGVKASQTGF VVLVLLQCCS AYKLVCYYTS WSQYREGDGS CFPDALDRFL CTHIIYSFAN ISNDHIDTWE WNDVTLYGML NTLKNRNPNL KTLLSVGGWN FGSQRFSKIA SNTQSRRTFI KSVPPFLRTH GFDGLDLAWL YPGRRDKQHF TTLIKEMKAE FIKEAQPGKK QLLLSAALSA GKVTIDSSYD IAKISQHLDF ISIMTYDFHG AWRGTTGHHS PLFRGQEDAS PDRFSNTDYA VGYMLRLGAP ASKLVMGIPT FGRSFTLASS ETGVGAPISG PGIPGRFTKE AGTLAYYEIC DFLRGATVHR ILGQQVPYAT KGNQWVGYDD QESVKSKVQY LKDRQLAGAM VWALDLDDFQ GSFCGQDLRF PLTNAIKDAL AATKLGPEQK LISEEDLNSA VDHHHHHH|
|Expression System||CHO cells|
|Method of Purification||CHI3L1 protein was purified using Protein G affinity chromatography|
|Form & Buffer||Supplied in liquid form in Phosphate-Buffered Saline (pH 7.4)|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. The glycoside hydrolase 18 family of chitinases includes eight human family members. CHI3L1 is a glycoprotein member of the glycosyl hydrolase 18 family. The protein lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. This protein is thought to play a role in the process of inflammation and tissue remodeling. Recombinant human CHI3L1 protein was expressed with C-terminal myc-His-tag in CHO(chinese hamster ovary) cells using mammalian expression system and purified by using conventional chromatography techniques.|
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