CHK1 antibody (10R-8604)

Mouse monoclonal CHK1 antibody

Synonyms Monoclonal CHK1 antibody, Anti-CHK1 antibody, CHEK1 antibody, checkpoint kinase 1 antibody, 2720 antibody, BOS_24586 antibody, C85740 antibody, cell cycle checkpoint kinase antibody, CH211-257I19.3 antibody, checkpoint kinase-1 antibody, checkpoint kinase 1 homolog antibody, Checkpoint antibody, S. pombe antibody, homolog of antibody, 1 antibody, chk1 antibody, CHK1 checkpoint homolog antibody, CHK1 checkpoint homolog (S. pombe) antibody, Chk1 checkpoint kinase antibody, Chk1-S antibody, rad27 antibody, rad27 homolog antibody, serine/threonine-protein kinase Chk1 antibody, xChk1 antibody
Cross Reactivity Human, Mouse, Rat
Applications IP, WB
Immunogen CHK1 antibody was raised in Mouse using a recombinant human protein purified from E.coli (His-CHK1) as the immunogen

Images

Western Blot analysis using CHK1 antibody (10R-8604)

Specifications

Host Mouse
Clone AF7H4
Isotype IgG1 kappa
Method of Purification CHK1 antibody was purified by ammonium sulfate precipitation
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:1000, IP: 1-2 ul

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance Check point kinase 1 (Chk1) is a serine / threonine protein kinase and a key mediator in the DNA damage-induced checkpoint network. Chk1 is an evolutionarily conserved protein kinase that functions to ensure genomic integrity upon genotoxic stress. When the G2 or S checkpoint is abrogated by the inhibition of Chk1, p53-deficient cancer cells undergo mitotic catastrophe and eventually apoptosis, whereas normal cells are still arrested in the G1 phase.

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Images

  • Western Blot analysis using CHK1 antibody (10R-8604) |

Availability: In stock

Price: $295.00
Size: 100 ul
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