CHK2 antibody (10R-8548)

Mouse monoclonal CHK2 antibody

Synonyms Monoclonal CHK2 antibody, Anti-CHK2 antibody, CHEK2 antibody, checkpoint kinase 2 antibody, BOS_16720 antibody, cds1 antibody, cds1 homolog antibody, CH211-207K7.3 antibody, checkpoint and tumor suppressor protein 2 antibody, checkpoint-like protein CHK2 antibody, CHK2 antibody, CHK2 checkpoint homolog antibody, CHK2 checkpoint homolog (S. pombe) antibody, fa66f08 antibody, hCds1 antibody, hucds1 antibody, LFS2 antibody, PP1425 antibody, protein kinase Cds1 antibody, protein kinase CHK2 antibody, Rad53 antibody, Rad53 homolog antibody, RP11-436C9.1 antibody, serine/threonine-protein kinase CHK2 antibody
Cross Reactivity Human
Applications ELISA, IP, WB
Immunogen CHK2 antibody was raised in Mouse using a recombinant human protein purified from E.coli(His-CHK2) as the immunogen

Images

Western Blot analysis using Chk2 antibody (10R-8548)

Specifications

Host Mouse
Clone 20A8
Isotype IgG1 kappa
Method of Purification CHK2 antibody was purified by ammonium sulfate precipitation
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:2000, IP: 1 ul

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance Both CHK1 and CHK2 are critically important checkpoint kinases. CHK1 is essential for normal development and cell growth and CHK1 deficiency in mouse or in embryonic stem (ES) cells is lethal. Loss of CHK2 is tolerated and has been found to be associated with a subset of Li-Fraumeni cases. Li-Fraumeni syndrome increases greatly the susceptibility to cancer, with particularly high occurrences of breast cancer, brain tumors, acute leukemia, soft tissue sarcomas, bone sarcomas, and adrenal cortical carcinoma.

References
Add a Paper

Sorry, but there are no references currently for this product.

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Images

  • Western Blot analysis using Chk2 antibody (10R-8548) |

Availability: In stock

Price: $295.00
Size: 100 ul
OR
Shipping
View Our Distributors