CHUK antibody (10R-1992)
Mouse monoclonal CHUK antibody
|Synonyms||Monoclonal CHUK antibody, Anti-CHUK antibody, Conserved helix-loop-helix ubiquitous kinase antibody|
|Immunogen||CHUK antibody was raised in Mouse using a purified recombinant fragment of CHUK(aa500-590) expressed in E. coli as the immunogen.|
Western Blot analysis using CHUK antibody (10R-1992)
Western Blot showing CHUK antibody used against truncated Trx-CHUK recombinant protein (1).
|Form & Buffer||Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.|
Usage & Assay Information
|Usage Recommendations||ELISA: 1:10,000, WB: 1:500-1:2000|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||CHUK is a member of the serine/threonine protein kinase family, CHUK is a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.|
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