Chymotrypsin antibody (10R-C129a)

Mouse monoclonal Chymotrypsin antibody

Synonyms Monoclonal Chymotrypsin antibody, Anti-Chymotrypsin antibody
Specificity Human chymotrypsin
Cross Reactivity To be determined by end-user
Applications ELISA, WB
Immunogen Chymotrypsin antibody was raised in mouse using purified human pancreatic chymotrypsin as the immunogen.

Specifications

Host Mouse
Clone 602
Isotype IgG3
Form & Buffer Supplied as a liquid in PBS, pH 7.4.
Concentration Batch dependent - please inquire should you have specific requirements

Usage & Assay Information

Usage Recommendations ELISA: 1:204,800

Storage & Safety

Storage Aliquot and store at -70 deg C or lower. Avoid repeated freeze/thaw cycles

General Information

Biological Significance Chymotrypsin is a digestive enzyme that can perform proteolysis. Chymotrypsin preferentially cleaves peptide amide bonds where the carboxyl side of the amide bond (the P1 position) is a tyrosine, tryptophan, or phenylalanine. These amino acids contain an aromatic ring in their sidechain that fits into a 'hydrophobic pocket' (the S1 position) of the enzyme. The hydrophobic and shape complementarity between the peptide substrate P1 sidechain and the enzyme S1 binding cavity accounts for the substrate specificity of this enzyme. Chymotrypsin also hydrolyzes other amide bonds in peptides at slower rates, particularly those containing leucine at the P1 position.

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Availability: In stock

Price: $425.00
Size: 500 ug
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