CIB1 protein (His tag) (80R-1039)

Purified recombinant Human CIB1 protein

Synonyms CIB protein, CIB 1, CIB1 protein, SIP2-28(SNK interacting protein2-28) protein, Calcium and integrin binding protein 1 protein, SNK interacting protein 2 to 28., CIB-1, Calcium and integrin binding 1 protein, CIB 1 protein, Human Snk interacting protein 2 to 28 mRNA complete cds protein, CIB-1 protein, Calcium and integrin binding 1 Calcium and integrin binding 1 (calmyrin) protein, CIB protein, PRKDCIP protein, KIP (Kinase interacting protein) protein, DNA PKcs interacting protein protein, CALMYRIN protein, SIP2 28 protein, Kinase interacting protein protein, CIB1
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of CIB1 protein (His tag) (80R-1039)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 1-191 amino acids: MGSSHHHHHH SSGLVPRGSH MGGSGSRLSK ELLAEYQDLT FLTKQEILLA HRRFCELLPQ EQRTVESSLR AQVPFEQILS LPELKANPFK ERICRVFSTS PAKDSLSFED FLDLLSVFSD TATPDIKSHY AFRIFDFDDD GTLNREDLSR LVNCLTGEGE DTRLSASEMK QLIDNILEES DIDRDGTINL SEFQHVISRS PDFASSFKIV L
Expression System E.coli
Purity > 95% pure
Molecular Weight 23 kDa (211aa), confirmed by MALDI-TOF.
Tag/Conjugate His tag
Form & Buffer Supplied as a liquid in 20mM Tris, pH 8.0, containing 5mM DTT.
Concentration 1 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels < 1.0 EU per ug of protein (determined by LAL method)

General Information

Biological Significance CIB, KIP (Kinase interacting protein), SIP2-28 (SNK interacting protein2-28). CIB1 (Calcium and integrin binding 1) is a regulatory protein with 50% homology to calmodulin and calcineurin B, that encodes a member of the calcium-binding protein family. The specific function of this protein has not yet been determined; however this protein is known to interact with DNA-dependent protein kinase and may play a role in kinase-phosphatase regulation of DNA end joining. Also CIB1 is widely expressed and binds to a number of effectors, such as PAK1, and polo-like kinases, in different tissues. Recombinant human CIB1, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

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Images

  • Coomassie Blue stained SDS-PAGE of CIB1 protein (His tag) (80R-1039) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: $255.00
Size: 100 ug
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