CK2beta protein (30R-1151)
Purified recombinant Human CK2beta protein
|Synonyms||PKCK2B protein, CK2beta, G5A protein, CK II beta protein, PKCK2 Beta protein, Casein Kinase 2B protein, CKbeta 2, Casein Kinase 2 beta protein, MGC138222 protein, G5A protein, Casein kinase II subunit beta protein, Phosvitin protein, Casein kinase 2 beta polypeptide protein, CKbeta 2 protein, CK2B protein, CSNK2B protein, CKbeta-2, CKbeta-2 protein, MGC138224 protein, CSK2B protein, CSNK 2B protein, Casein Kinase 2 beta protein, CK2N protein,|
Coomassie Blue stained SDS-PAGE of CK2beta protein (30R-1151)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-215 amino acids: MSSSEEVSWI SWFCGLRGNE FFCEVDEDYI QDKFNLTGLN EQVPHYRQAL DMILDLEPDE ELEDNPNQSD LIEQAAEMLY GLIHARYILT NRGIAQMLEK YQQGDFGYCP RVYCENQPML PIGLSDIPGE AMVKLYCPKC MDVYTPKSSR HHHTDGAYFG TGFPHMLFMV HPEYRPKRPA NQFVPRLYGF KIHPMAYQLQ LQAASNFKSP VKTIR|
|Purity||> 95% pure|
|Molecular Weight||24.9 kDa (215aa), confirmed by MALDI-TOF.|
|Form & Buffer||Liquid. 20mM Tris pH 8.0, 10% glycerol, 0.2M NaCl, 1mM DTT, 1mM EDTA|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||Casein Kinase 2 (CK2, also called PKCK2) is a ubiquitous Ser/Thr kinase expressed in all eukaryotes. CK2 is a tetramer composed of two catalytic kinase domains, alpha subunits, and two identical regulatory beta subunits. It has been implicated in cell cycle control, DNA repair, regulation of the circadian rhythm, and other cellular processes. The beta subunit itself does not have kinase activity, but confers stability to the CK2 alpha subunit and is involved in activity and substrate specificity. Recombinant human CK2beta was expressed in E. coli and purified by using conventional chromatography techniques.|
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