CKMB antibody (10R-C146a)
Mouse monoclonal CKMB antibody
Overview
Overview
| Synonyms | Monoclonal CKMB antibody, Anti-CKMB antibody, Creatine Kinase-MB Isoenzyme antibody, CK-MB antibody |
|---|---|
| Specificity | Human |
| Cross Reactivity | No cross reactivity withCKBB or CKMM in ELISA |
| Applications | User optimized |
| Immunogen | CKMB antibody was raised in mouse using purified human CK-MB as the immunogen. |
Specifications
| Host | Mouse |
|---|---|
| Clone | 9 |
| Isotype | IgG1 kappa |
| Form & Buffer | Protein G purified and supplied in PBS, pH 7.3, with 0.05% NaN3. |
| Concentration | Batch dependent - please inquire should you have specific requirements |
Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
|---|---|
| Biohazard Information | This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. |
General Information
| Biological Significance | Creatine kinase (CK) is an enzyme expressed by various tissues and cell types. CK catalyses the conversion of creatine and consumes adenosine triphosphate (ATP) to create phosphocreatine and adenosine diphosphate (ADP). This CK enzyme reaction is reversible, such that also ATP can be generated from PCr and ADP. In the cells, the "cytosolic" CK enzymes consist of two subunits, which can be either B (brain type) or M (muscle type). There are, therefore, three different isoenzymes: CK-MM, CK-BB and CK-MB. |
|---|
References
References
Multiplex immunoassays on size-categorized individual beads using time-resolved fluorescence
Analytica Chimica Acta
Volume: 410
Issue: 1-2
Page: 85-96
DOI: 10.1016/S0003-2670(00)00722-4
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