CKS2 protein (T7 tag) (80R-1070)
Purified recombinant Human CKS2 protein (T7 tag)
|Synonyms||CKS 2, CKS 2 protein, Cyclin-dependent kinases regulatory subunit 2 CDC28 protein kinase regulatory subunit 2 protein, CKSHS2 protein, CKS2, cerevisiae Cdc28/Cdc2 kinase subunit) homolog 2 protein, CKS-2, Cyclin-dependent kinases regulatory subunit 2 protein, CKS 2 protein, Cyclin dependent kinases regulatory subunit 2., CDC28 Protein kinase 2 protein, CKS1(S protein, CKS-2 protein, CKS2 protein|
Coomassie Blue stained SDS-PAGE of CKS2 protein (T7 tag) (80R-1070)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-79 amino acids: MASMTGGQQM GRGSHMAHKQ IYYSDKYFDE HYEYRHVMLP RELSKQVPKT HLMSEEEWRR LGVQQSLGWV HYMIHEPEPH ILLFRRPLPK DQQK|
|Purity||> 95% pure|
|Molecular Weight||11.3 kDa (94aa), confirmed by MALDI-TOF.|
|Form & Buffer||Supplied as a liquid in PBS, pH 7.4, containing 40% glycerol, 2mM DTT, 0.1mM PMSF, and 1mM EDTA.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||CKS2, also known as CDC28 Protein kinase 2 associates with the catalytic subunit of cyclin-dependent kinases and has therefore been assumed to play a direct role in cell cycle regulation. The function of CKS2 in somatic mammalian cells is not well understood although it is required for the first metaphase/anaphase transition during the meiosis. Emerging evidence shows that elevated expression of CKS2 protects the cells from apoptosis. Recombinant CKS2 fused with T7-tag was expressed in E. coli and purified by conventional chromatography techniques.|
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