CNPY3 protein (His tag) (80R-2698)
Purified recombinant CNPY3 protein (His tag)
|Synonyms||Canopy 3 homolog protein, CAG4A protein, ERDA5 protein, PRAT4A protein, TNRC5 protein, CNPY3, CNPY 3, CNPY-3, CNPY 3 protein, CNPY-3 protein|
SDS-PAGE analysis of CNPY3 protein (His tag) (80R-2698)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||31-278 aa: MGSSHHHHHH SSGLVPRGSH MGSGPSQAGA EENDWVRLPS KCEVCKYVAV ELKSAFEETG KTKEVIGTGY GILDQKASGV KYTKSDLRLI EVTETICKRL LDYSLHKERT GSNRFAKGMS ETFETLHNLV HKGVKVVMDI PYELWNETSA EVADLKKQCD VLVEEFEEVI EDWYRNHQEE DLTEFLCANH VLKGKDTSCL AEQWSGKKGD TAALGGKKSK KKSSRAKAAG GRSSSSKQRK ELGGLEGDPS PEEDEGIQKA SPLTHSPPDE L|
|Purity||> 85% pure|
|Molecular Weight||29.9 kDa|
|Form & Buffer||Supplied in liquid form in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT|
Storage & Safety
|Storage||Can be stored at 4 deg C for short terms (1-2 weeks). For long term storage, aliquot and store at -20 deg C or -70 deg C. Avoid repeated freezing and thawing cycles|
|Biological Significance||Canopy 3 homolog, also known as CNPY3, is Toll-like receptor (TLR)-specific co-chaperone for HSP90B1. This protein is required for proper TLR folding, except that of TLR3, and hence controls TLR exit from the endoplasmic reticulum. Consequently, CNPY3i s required for both innate and adaptive immune responses. Recombinant human CNPY3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.|
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