CNTF protein (30R-2079)

Purified recombinant CNTF protein

Synonyms Ciliary neurotrophic factor protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE
Assay Information CNTF protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

Images

Coomassie Blue stained SDS-PAGE of CNTF protein (30R-2079)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 1-200 amino acids: MAFTEHSPLT PHRRDLCSRS IWLARKIRSD LTALTESYVK HQGLNKNINL DSADGMPVAS TDQWSELTEA ERLQENLQAY RTFHVLLARL LEDQQVHFTP TEGDFHQAIH TLLLQVAAFA YQIEELMILL EYKIPRNEAD GMPINVGDGG LFEKKLWGLK VLQELSQWTV RSIHDLRFIS SHQTGIPARG SHYIANNKKM
Expression System E.coli
Purity > 90% pure
Molecular Weight 22.9 kDa
Form & Buffer Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, with 1mM DTT, and 10% glycerol.
Concentration 1 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C or -70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance CNTF (Ciliary neurotrophic factor) is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. This protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. CNTF protein is structurally related to leukemia inhibitory factor (LIF), interleukin-6 (IL-6), interleukin-11 (IL-11) and oncostatin M (OSM). It is localized in the cell nucleus subsequent to receptor binding. Recombinant human CNTF protein was expressed in E.coli and purified by using conventional chromatography techniques.

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Images

  • Coomassie Blue stained SDS-PAGE of CNTF protein (30R-2079) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: $255.00
Size: 100 ug
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