CNTF protein (30R-AC014)

Purified recombinant Human CNTF protein

Synonyms Ciliary Neurotrophic Factor protein
Species Human
Protein Type Recombinant
Applications User optimized

Specifications

Residues Region of CNTF protein corresponding to amino acids MAFTEHSPLT PHRRDLCSRS IWLARKLRSD LTALTESYVK HQGLNKNINL DSADGMPVAS TDQWSELTEA ERLQENLQAY RTFHVLLARL LEDQQVHFTP TEGDFHQAIH TLLLQVAAFA YQIEELMILL EYKIPRNEAD GMPINVGDGG LFEKKLWGLK VLQELSQWTV RSIHDLRFIS SHQTGIPARG SHYIANNKKM.
Expression System E.coli
Purity > 98% pure
Molecular Weight 22.7 kDa
Form & Buffer Lyophilized from 5mM NaPO4, pH 7.0, with 75mM NaCl. Reconstitute in 5mM Sodium Phosphate, pH 7.5 to a concentration of 0.1- 1.0 mg/ml.

Usage & Assay Information

Bioactivity The ED50 as determined by the dose-dependent proliferation of human TF-1 cells is 5 x 10^5 units/mg.

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

General Information

Biological Significance CNTF is a potent neural factor that was originally characterized as a vital factor for the survival of chick ciliary neurons in vitro. CNTF is also important for the survival of other neural cell types including primary sensory neurons, motor neurons, basal forebrain neurons and type 2 astrocytes. CNTF is highly conserved across species and exhibits cross-species bioactivity.

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Availability: In stock

Price: $225.00
Size: 20 ug
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