CNTFR Blocking Peptide (33R-1094)

A synthetic peptide for use as a blocking control in assays to test for specificity of CNTFR antibody, catalog no. 70R-9962

Synonyms CNTFR control peptide, CNTFR antibody Blocking Peptide, Anti-CNTFR Blocking Peptide, ciliary neurotrophic factor receptor Blocking Peptide, MGC1774 Blocking Peptide
Protein Type Synthetic
Applications IHC, WB

Specifications

Residues ADIIGYVASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSRLR
Molecular Weight 25 kDa
Form & Buffer Lyophilized powder. Add 100ul of distilled water for a final peptide concentration is 1 mg/ml.

Storage & Safety

Storage Store at -20 deg C long term. Avoid repeat freeze-thaw cycles.

General Information

Biological Significance This gene encodes a hematopoeitin/interferon-class receptor belonging to the cytokine superfamily of receptors. The encoded gene product represents the CNTF-specific alpha subunit of a heterotrimer forming the CNTF receptor complex, which also includes LIFR and gp130. The receptor is attached to the membrane by a glycosyl-phosphatidylinositol linkage and contains an immunoglobulin-like C2-type domain and a fibronectin type-III domain. Signal transduction requires that CNTF bind first to this alpha component, which permits the recruitment of gp130 and LIFR beta to form the tripartite receptor complex. Signal transduction stimulates gene expression, cell survival or differentiation in a variety of neuronal cell types.

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Availability: In stock

Price: $130.00
Size: 100 ug
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