COBRA1 antibody (10R-8357)

Mouse monoclonal COBRA1 antibody

Synonyms Monoclonal COBRA1 antibody, Anti-COBRA1 antibody, COBRA 1 antibody, COBRA-1 antibody, COBRA1, Cofactor of BRCA1 antibody, NELFB antibody, Negative elongation factor B antibody
Applications WB

Images

Western Blot analysis using COBRA1 antibody (10R-8357)

Western blot of neonatal rat brain lysate showing specific immunolabeling of ~ 62K COBRA1 protein

Specifications

Host Mouse
Clone F7E4
Isotype IgG1
Method of Purification COBRA1 antibody was purified by Protein G affinity chromatography
Form & Buffer Supplied in liquid form in 10 mM HEPES buffer (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:1000

General Information

Biological Significance COBRA1 is an essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. May be able to induce chromatin unfolding

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Images

  • Western Blot analysis using COBRA1 antibody (10R-8357) | Western blot of neonatal rat brain lysate showing specific immunolabeling of ~ 62K COBRA1 protein

Availability: In stock

Price: $335.00
Size: 100 ul
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