COIL antibody (10R-1744)

Mouse monoclonal COIL antibody

Synonyms Monoclonal COIL antibody, Anti-COIL antibody, p80-coilin antibody, CLN80 antibody, Coilin p80 antibody
Specificity Human COIL
Cross Reactivity Human. Other species not studied
Applications Dot Blot, ICC
Immunogen COIL antibody was raised in mouse using recombinant Human Coilin (Coil)

Images

Western blot analysis using COIL antibody (10R-1744)

Specifications

Host Mouse
Clone 2196C5a
Isotype IgG1
Method of Purification COIL antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Form & Buffer COIL antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3 ).
Concentration 100 ug/ml

Usage & Assay Information

Usage Recommendations To be optimized by the end user.

Storage & Safety

Storage Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing.
Biohazard Information This antibody solution contains sodium azide (NaN ) as a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water. It is strongly adv

General Information

Biological Significance The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14.

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Images

  • Western blot analysis using COIL antibody (10R-1744) |

Availability: In stock

Price: $190.00
Size: 50 ug
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