Collagen Type I alpha 2 antibody (70R-5422)

Rabbit polyclonal Collagen Type I alpha 2 antibody raised against the middle region of COL1A2

Synonyms Polyclonal Collagen Type I alpha 2 antibody, Anti-Collagen Type I alpha 2 antibody, Collagen Type 1 antibody, COL1A2 antibody, OI4 antibody, Collagen type I alpha 1 antibody, Collagen Of Skin Tendon And Bone antibody, Collagen type I alpha 2 antibody, Osteogenesis Imperfecta Type IV antibody
Specificity Collagen Type I alpha 2 antibody was raised against the middle region of COL1A2
Cross Reactivity Human, Dog, Rat, Mouse, Rabbit, Bovine, Chicken, African clawed frog
Applications WB
Immunogen Collagen Type I alpha 2 antibody was raised using the middle region of COL1A2 corresponding to a region with amino acids PGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGPPG
Assay Information Collagen Type I alpha 2 Blocking Peptide, catalog no. 33R-7134, is also available for use as a blocking control in assays to test for specificity of this Collagen Type I alpha 2 antibody

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Western Blot analysis using Collagen Type I alpha 2 antibody (70R-5422)

Collagen Type I alpha 2 antibody (70R-5422) used at 1 ug/ml to detect target protein.

Specifications

Host Rabbit
Method of Purification Affinity purified
Molecular Weight 150 kDa (MW of target protein)
Form & Buffer Lyophilized powder. Add 50ul distilled water for a 1mg/ml concentration of COL1A2 antibody in PBS
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1 ug/ml

Storage & Safety

Storage Store at 2-8 deg C for short periods. For longer periods of storage, store at -20 deg C. Avoid repeat freeze-thaw cycles.

General Information

Biological Significance COL1A2 is the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity.

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  • Western Blot analysis using Collagen Type I alpha 2 antibody (70R-5422) | Collagen Type I alpha 2 antibody (70R-5422) used at 1 ug/ml to detect target protein.

Availability: In stock

Price: $375.00
Size: 50 ug
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