Collagen Type III protein (30R-AC017)
Purified native Human Collagen Type III protein
|Synonyms||Fetal collagen protein, Collagen type III alpha 1 protein, Ehlers Danlos syndrome type IV, Collagen type III alpha protein, autosomal dominant protein, EDS4A protein|
Western Blot analysis using Collagen Type III protein (30R-AC017)
Lane 1: Human Collagen III. Load: 100 ng per lane. Primary antibody: Collagen III antibody at 1:1000 ON at 4 deg C. Secondary antibody: Dylight (TM) 649 Goat anti-rabbit at 1:20, 000 for 30 min at RT. Block for 30 min at RT.
|Method of Purification||Collagen Type III protein was purified by affinity chromatography.|
|Form & Buffer||Sterile filtered liquid in 0.5M CH3COOH, with 0.01% NaN3.|
|Concentration||Batch dependent - please inquire should you have specific requirements|
Storage & Safety
|Storage||Store at 4 deg C. Dilute only prior to immediate use.|
|Biohazard Information||This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.|
|Biological Significance||Collagen III is a fibrillar collagen that is found in extensible connective tissues such as skin, lung, and the vascular system, frequently in association with type I Collagen. Mutations in the gene are associated with Ehlers Danlos syndrome type IV, and with aortic and arterial aneurysms. Although alternate transcripts have been detected for this gene, they are the result of mutations; these mutations alter splicing, often leading to the exclusion of multiple exons.|
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