Collagen Type IV protein (30R-AC018)

Purified native Human Collagen Type IV protein

Synonyms Canstatin protein, Arresten protein, Collagen Of Basement Membrane alpha 1 Chain protein
Species Human
Protein Type Native
Applications User optimized

Specifications

Source Human placenta
Method of Purification Collagen Type IV protein was purified by affinity chromatography.
Form & Buffer Sterile filtered liquid in 0.5M CH3COOH, with 0.01% NaN3.
Concentration Batch dependent - please inquire should you have specific requirements

Storage & Safety

Storage Store at 4 deg C. Dilute only prior to immediate use.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

General Information

Biological Significance Collagen IV is a major constituent of the basement membranes along with laminins, proteoglycans and enactins. It is a multimeric protein composed of 3 alpha subunits. These subunits are encoded by 6 different genes, alpha 1 through alpha 6, each of which can form a triple helix structure with 2 other subunits to form type IV collagen. It can form insoluble fibers with high tensile strength. Collagen IV is useful in detecting the loss of parts of basement membranes in carcinomas.

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Price: $497.00
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