Complement C1 protein (32C-CP1093)

Purified Complement C1 protein isolated from human plasma

Synonyms C1 protein
Species Human
Protein Type Native

Specifications

Source Human serum/plasma
Molecular Weight 766 kDa
Form & Buffer 0.2 um filtered frozen liquid in 50mM NaAcetate, 50mM EACA, 10mM Benzamidine, 10mM EDTA, 300mM NaCl and 40% Glycerol, pH 5.5, with no presveratives added.

Usage & Assay Information

Bioactivity >250,000 C1H50 units/mg total protein

Storage & Safety

Storage Aliquot and store at -70 deg C or lower. Avoid repeated freeze/thaw cycles.
Biohazard Information Donor samples were tested and found to be negative for HBsAg, HTLV-I/II, STS, and for antibodies to HCV, HIV-1 and HIV-II. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.

General Information

Biological Significance C1 is the first complement component in the cascade referred to as the classical pathway of complement. C1 binds to and is activated by antibodies bound to antigens (immune complexes) yielding a protease that initiates the cascade. C1 is actually a non-covalent complex of three different proteins (C1q, C1r and C1s) bound together in a calcium-dependent complex.

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Availability: In stock

Price: $370.80
Size: 200 ug
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