Complement C3 antibody (20C-CR2018S)

Sheep polyclonal Complement C3 antibody

Synonyms Polyclonal Complement C3 antibody, Anti-Complement C3 antibody, Complement C 3 antibody, Complement C -3, C3 antibody, Complement C 3, Complement C -3 antibody, Complement C3
Specificity Human
Cross Reactivity To be determined by end-user
Applications User optimized
Immunogen Complement C3 antibody was raised in sheep using purified complement C3 isolated from human plasma as the immunogen.

Specifications

Host Sheep
Form & Buffer Delipidated antiserum, with 0.1% NaN3.

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.

General Information

Biological Significance Native human C3 is a naturally glycosylated (~2.7%) polypeptide containing two disulfide-linked chains. C3 is central to the activation of all three pathways of complement activation. Initiation of each pathway generates proteolytic enzyme complexes (C3 convertases) which are bound to the target surface. These enzymes cleave a peptide bond in C3 releasing the anaphylatoxin C3a and activating C3b. For a brief time (~60 us) this nascent C3b is capable of reacting with and covalently coupling to hydroxyl groups on the target surface.

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Availability: In stock

Price: $168.00
Size: 1 ml
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