Complement C3b beta antibody (10R-C194a)

Mouse monoclonal Complement C3b beta antibody

Synonyms Monoclonal Complement C3b beta antibody, Anti-Complement C3b beta antibody, Complement Cb 3, C3b beta antibody, Complement Cb -3, Complement Cb -3 antibody, Complement C3b, Complement Cb 3 antibody
Specificity Human complement C3b beta
Cross Reactivity To be determined by end-user
Applications IHC-F, WB
Immunogen Complement C3b beta antibody was raised in mouse using human complement component C3 as the immunogen.

Specifications

Host Mouse
Clone H11
Isotype IgG1
Method of Purification Protein A affinity chromatography
Form & Buffer Supplied as a lyophilized powder. Reconstitute in 1 ml dist. water (final solution contains 0.09 % NaN3, 0.5% BSA in PBS buffer, pH 7.4)

Usage & Assay Information

Usage Recommendations IHC-F: 1:10

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze-thaw cycles.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

General Information

Biological Significance C3b is the larger of two elements formed by the cleavage of complement component 3. C3b covalently bonds to microbial cell surfaces within an organism's body. This leads to the production of surface-bound C3 convertase and thus more C3b components. Bound C3b also aids in opsonization of the microbe by macrophages.

References
Add a Paper

Christopher Premanandana, Craig A. Storozuka, Corey D. Clayb, Michael D. Lairmorea, Larry S. Schlesingera, Andrew J. Phipps

Complement protein C3 binding to Bacillus anthracis spores enhances phagocytosis by human macrophages

Microbial Pathogenesis

Volume: 46 Issue: 6 Page: 306-314 DOI: 10.1016/j.micpath.2009.03.004

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Availability: In stock

Price: $295.00
Size: 50 ug
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