Complement C5b, 6 complex protein (32C-CP2031U)

Purified native Complement C5b, 6 complex protein

Synonyms Anaphylatoxin C5b protein, C5 protein, Complement C5 protein, Complement C5b protein, Complement C5 precursor protein, Complement component 5 protein, CPAMD4 protein, C5b6 protein
Species Human
Protein Type Native


Source Normal human serum
Molecular Weight 285 kDa
Form & Buffer Supplied as a frozen liquid with 10 mM HEPES and 120 mM NaCl, pH 7.2
Concentration 0.2 mg/ml

Storage & Safety

Storage Store at -70 deg C or below. Avoid freeze/thaw cycles.
Biohazard Information This protein is purified from human plasma, therefore precautions appropriate for handling any blood-derived product must be use.

General Information

Biological Significance Complement C5b, 6 complex, is a product of complement activation of C5 and an intermediate in the formation of the C5b-9 membrane attack complex (MAC) of complement. Each pathway of complement generates proteolytic enzyme complexes (C3/C5 convertases) which are bound to the target surface. These enzymes cleave a peptide bond in the larger alpha chain of C5 releasing the highly potent anaphylatoxin C5a (74 amino acids) and activating C5b.This is the only proteolytic step in the assembly of the C5b-9 complex.

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Availability: In stock

Price: $428.80
Size: 50 ug
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