Complement Factor B (30C-CP2036U)

Purified native Human Complement Factor B

Synonyms Native CFB
Species Human
Protein Type Native
Applications User optimized


Source Human serum/plasma
Purity > 98% pure
Molecular Weight 93 kDa
Form & Buffer Supplied as a liquid in PBS, pH 7.2, no preservatives added,
Concentration 1.0 mg/ml

Usage & Assay Information

Bioactivity 4, 700 U/mg - 100 % of factor B activity in NHS on a mg/mg basis

Storage & Safety

Storage Aliquot and store at -70 deg C or lower. Avoid repeated freeze/thaw cycles.
Biohazard Information Donor samples were tested and found to be negative for HBsAg, HTLV-I/II, STS, and for antibodies to HCV, HIV-1 and HIV-II. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.

General Information

Biological Significance Complement factor B is a glycosylated protein composed of a single 93,000 Da polypeptide chain. It is an essential component of the alternative pathway of complement activation and is found in plasma at approximately 200 ug/mL. In the presence of Mg++ factor B binds to C3b and the C3b,B complex can be activated by factor D, a serine protease that circulates as an active trypsin-like serine protease.

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Availability: In stock

Price: $370.80
Size: 250 ug
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