Complement Factor C9 antibody (10R-8451)

Mouse monoclonal Complement Factor C9 antibody

Synonyms Monoclonal Complement Factor C9 antibody, Anti-Complement Factor C9 antibody, C9 antibody, complement component 9 antibody, complement component C9 antibody, complement protein C9 antibody
Cross Reactivity Human
Applications WB
Immunogen Complement Factor C9 antibody was raised in Mouse using a protein purified from Human plasma as the immunogen

Images

Western Blot analysis using Complement factor C9 antibody (10R-8451)

Specifications

Host Mouse
Clone 64E9
Isotype IgG1 kappa
Method of Purification Complement Factor C9 antibody was purified by ammonium sulfate precipitation
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:2000

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance Complement Factor C9, 71 kDa, is the last of the human complement components creating the membrane attack complex (MAC). Activation of the complement system leads to the formation of the MAC, which in turn causes lysis, and death of target cells. C9 plays an important role in inflammatory reactions since it is essential for lytic action of the MAC. Such lytic action could be the basis for complement autotoxicity. Like most of the complement components, C9 belongs to the acute-phase proteins which are generally of hepatic origin, and their plasma concentrations increase (or decrease) following tissue injury and inflammation. Also, because C9 is required for the MAC of complement to become functional, interfering with signaling pathways that stimulate its production could offer new therapeutic strategies for treating various neurodegenerative disorders.

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Images

  • Western Blot analysis using Complement factor C9 antibody (10R-8451) |

Availability: In stock

Price: $295.00
Size: 100 ul
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