Complement Factor H antibody (10R-8432)

Mouse monoclonal Complement Factor H antibody

Synonyms Monoclonal Complement Factor H antibody, Anti-Complement Factor H antibody, CFH antibody, complement factor H antibody, adrenomedullin binding protein antibody, age-related maculopathy susceptibility 1 antibody, AHUS1 antibody, AMBP1 antibody, ARMD4 antibody, arms1 antibody, beta-1H antibody, beta-1-H-globulin antibody, BOS_15597 antibody, cfhl3 antibody, complement component factor H antibody, complement factor H related protein 3A4/5G4 antibody, complement inhibitory factor H antibody, complement regulator factor H antibody, factor H antibody, factor H-like 1 antibody, FH antibody, FHL1 antibody, HF antibody, hf1 antibody, hf2 antibody, H factor 1 (complement) antibody, H factor 2 (complement) antibody, HUS antibody, Mud-1 antibody, NOM antibody, platelet complement factor H antibody, protein beta-1-H antibody, RP1-177P10.1 antibody, Sas1 antibody, Sas-1 antibody
Cross Reactivity Human
Applications ELISA, IP
Immunogen Complement Factor H antibody was raised in Mouse using a protein purified from Human plasma as the immunogen

Images

Western Blot analysis using Complement Factor H antibody (10R-8432)

Specifications

Host Mouse
Clone 63G5
Isotype IgG2b kappa
Method of Purification Complement Factor H antibody was purified by ammonium sulfate precipitation
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations IP: 1 ul

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance Factor H is a member of the regulators of complement activation family and is a complement control protein. It is a large (155 kilodaltons), soluble glycoprotein that circulates in human plasma (at typical concentrations of 200?300 micrograms per milliliter[1]). Its principal function is to regulate the Alternative Pathway of the complement system, ensuring that the complement system is directed towards pathogens or other dangerous material and does not damage host tissue. Factor H regulates complement activation on self cells and surfaces by possessing both cofactor activity for the Factor I mediated C3b cleavage, and decay accelerating activity against the alternative pathway C3 convertase, C3bBb. Factor H exerts its protective action on self cells and self surfaces but not on the surfaces of bacteria or viruses, because it binds to glycosaminoglycans (GAGs) that are generally present on host cells but not, normally, on pathogen surfaces.

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Images

  • Western Blot analysis using Complement Factor H antibody (10R-8432) |

Availability: In stock

Price: $295.00
Size: 100 ul
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