CRABP2 antibody (10R-1131)
Mouse monoclonal CRABP2 antibody
Overview
Overview
Synonyms | Monoclonal CRABP2 antibody, Anti-CRABP2 antibody, Cellular retinoic acid binding protein 2 antibody, antibody, CRABP II antibody, CRABP2 antibody, Cellular retinoic acid binding protein 2 Cellular retinoic acid binding protein II antibody, RBP6 antibody, CRABP 2, CRABP2, CRABP-II antibody, CRABP -2 antibody, CRABP 2 antibody, CRABP-II antibody, CRABP -2, RBP6 antibody, CRABPII antibody |
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Specificity | Human |
Cross Reactivity | Human, Mouse |
Applications | ELISA, WB |
Immunogen | CRABP2 antibody was raised in mouse using recombinant human CRABP2 (1-138aa) purified from E. coli as the immunogen. |
Images
Western Blot analysis of CRABP2 antibody (10R-1131)
Cell lysates of mouse eye (60 ug) were resolved by SDS-PAGE, transferred to nitrocellulose membrane and probed with anti-human CRABP2 (1:250). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
Specifications
Host | Mouse |
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Clone | AT2E11 |
Isotype | IgG2a kappa |
Source | Anti-human CRABP2 antibody, clone AT2E11, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CRABP2 protein. |
Method of Purification | CRABP2 antibody was purified by protein-G affinity chromatography |
Form & Buffer | Supplied as a liquid in PBS, pH 7.4, with 0.1% NaN3. |
Concentration | 1 mg/ml |
Usage & Assay Information
Usage Recommendations | WB: 1:250-1:1,000 |
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Storage & Safety
Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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General Information
Biological Significance | The cellular retinoic acid-binding protein II (CRABP-II) is involved in the conversion of vitamin A into its intracellular active form retinoic acid, which regulates the genes responsible for lipid metabolism and adipocyte differentiation. CRABP2 gene is located on chromosome 1q21-23 and this region has been linked with related disorders such as familial combined hyperlipidemia (FCHL) and type 2 diabetes mellitus. |
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