CSE1L antibody (10R-1628)

Mouse monoclonal CSE1L antibody

Synonyms Monoclonal CSE1L antibody, Anti-CSE1L antibody, MGC130036 antibody, CSEL 1 antibody, CSEL-1, CSE1L, XPO2 antibody, CSEL 1, CAS antibody, CSEL-1 antibody, CSE1 antibody, MGC130037 antibody, CSE1 chromosome segregation 1-like antibody, MGC117283 antibody
Specificity Human CSE1L
Cross Reactivity Human, Mouse, Rat. Other species not studied
Applications Dot Blot, ICC, WB
Immunogen CSE1L antibody was raised in mouse using recombinant Human Cse1 Chromosome Segregation 1-Like (Yeast) (Cse1L)

Images

Immunofluorescent staining using CSE1L antibody (10R-1628)

Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.01% Triton-X100 in PBS. The cells were immunostained with anti-CSE1L antibody.

Specifications

Host Mouse
Clone 2218C5a
Isotype IgG2a
Method of Purification CSE1L antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Form & Buffer CSE1L antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3 ).
Concentration 100 ug/ml

Usage & Assay Information

Usage Recommendations WB: 0.2-2 ug/ml

Storage & Safety

Storage Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing.
Biohazard Information This antibody solution contains sodium azide (NaN ) as a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water. It is strongly adv

General Information

Biological Significance Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importinalpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation.

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Images

  • Immunofluorescent staining using CSE1L antibody (10R-1628) | Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.01% Triton-X100 in PBS. The cells were immunostained with anti-CSE1L antibody.
  • Western Blot analysis of immunized recombinant protein using CSE1L antibody (10R-1628)

Availability: In stock

Price: $190.00
Size: 50 ug
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