CSE1L antibody (70R-10430)

Affinity purified rabbit polyclonal CSE1L antibody

Synonyms Polyclonal CSE1L antibody, Anti-CSE1L antibody, CAS antibody, MGC130036 antibody, MGC117283 antibody, MGC130037 antibody, CSE1 antibody, XPO2 antibody, CSEL 1 antibody, yeast antibody, CSEL-1 antibody, CSE1L, CSEL-1, CSEL 1, CSE1 chromosome segregation 1-like
Cross Reactivity Human, Mouse, Rat, Zebrafish, Bovine, African Clawed Frog, Chicken
Applications WB
Immunogen CSE1L antibody was raised in rabbit using the N terminal of CSE1L as the immunogen
Assay Information CSE1L Blocking Peptide, catalog no. 33R-2571, is also available for use as a blocking control in assays to test for specificity of this CSE1L antibody

Images

Western Blot analysis using CSE1L antibody (70R-10430)

CSE1L antibody (70R-10430) used at 0.2-1 ug/ml to detect target protein.

Specifications

Host Rabbit
Form & Buffer Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 0.2-1 ug/ml

Storage & Safety

Storage Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.

General Information

Biological Significance Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. CSE1L binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the protein may play a role both in apoptosis and in cell proliferation.

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Images

  • Western Blot analysis using CSE1L antibody (70R-10430) | CSE1L antibody (70R-10430) used at 0.2-1 ug/ml to detect target protein.

Availability: In stock

Price: $345.00
Size: 50 ug
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